Fig. 2. Etanercept protects against the induction of mRNA expression of adhesion-associated molecules. At 0, 3, 6, 24, and 72 h after cecum cauterization, cecal specimens were sampled to measure the mRNA levels of tumor necrosis factor (Tnf) (A), interleukin-6 transcript (Il6) (B), chemokine (C-X-C motif) ligand 2 transcript (Cxcl2) (C), and plasminogen activator inhibitor-1transcript (Pai1) (D). Data are presented as mean ± SEM. *p<0.05 indicated statistically significant differences. Three mice were used for each experimental group. We performed the experiments three times or more with similar results.